Dr. Debashish Ghose

Education

Work Experience

Research Interests

• 1. QbD assisted analytical and formulation of various novel nano formulations with poor solubility 2. Development of novel nanoparticulate systems for BCS Class II and IV drugs 3. Intra nasal Drug delivery systems for brain targeting

Publications

1. Swain SK, Maharana RL, Mahapatra SK, Ghose D, Jena BR. Quality By Design Enabled Carvedilol Self-Nanoemulsifying Drug Delivery System: In-Vitro and In-Vivo Characterization for Improved Management of Hypertension. BSCM [internet]. 2025 Sep. 2 [cited 2025 Dec. 26];64(4):277-95. available from: https://he01.tci-thaijo.org/index.php/CMMJ-MedCMJ/article/view/277010
2. Panigrahi, D., Swain, S., Sahu, P. Kumar, Ghose, D., Jena, B. R. Quality by design enabled formulation development of regorafenib monohydrate loaded PEGylated PLGA polymeric nanoparticles: Enhanced oral bioavailability and biopharmaceutical attributes. Nanomedicine Journal, 2024; 11(4): 401-416. doi: 10.22038/nmj.2024.76842.1867
3. Debashish Ghose, Suryakanta Swain, Chinam Niranjan Patra, Bikash Ranjan Jena, RP-UFLC based Bioanalytical Method Development, Optimization, andValidation for the Estimation of Isradipine in Rabbit Serum, Current Analytical Chemistry; Volume 19, Issue 5, Year 2023, e050623217647. DOI: 10.2174/1573411019666230605112048
4. KOMATI, S., BHANOJI RAO, M. E., SWAIN, S., & GHOSE, D. (2023). QUALITY BY DESIGN-DRIVEN FORMULATION DEVELOPMENT AND OPTIMIZATION OF ENALAPRIL MALEATE LOADED MUCOADHESIVE MICROSPHERES: IN VITRO AND IN VIVO CHARACTERIZATION. International Journal of Applied Pharmaceutics, 15(4), 266–276. https://doi.org/10.22159/ijap.2023v15i4.47905
5. Sasikanth Kothamasu, Surya Kanta Swain, Debashish Ghose, Muddana Eswara Bhanoji Rao, Bikash Ranjan Jena. Quality by Design Enabled Formulation Development, and Optimization of Floating Microballoons of Sildenafil Citrate: In Vitro and In Vivo Characterization,Eur. Chem. Bull. 2023,12(4), 1472-1515.
6. Suryakanta Swain, Debashish Ghose, Bikash Ranjan Jena*, GSN Koteswara Rao and Abhisek Sahu. Modern Advancements, Patents and Applications of Futuristic Nanozymes: A Comprehensive Review.Nanoscience & Nanotechnology-Asia; Volume 13, Issue 2, 2023 Published on: 22 May, 2023 Article ID: e300323215258Pages:DOI: 10.2174/2210681213666230330165806
7. Debashish Ghose*,Ch. Niranjan Patra, Surya Kanta Swain. QbD-based Formulation Development and Characterization of Isradipine Loaded Freeze-Dried Nanoparticles . (2023). Journal of Pharmaceutical Negative Results, 451-465. https://doi.org/10.47750/pnr.2023.14.03.056
8. GHOSE, D., PATRA, C. N., SWAIN, S., & SRUTI, J. (2023). BOX-BEHNKEN DESIGN-BASED DEVELOPMENT AND CHARACTERIZATION OF POLYMERIC FREEZE-DRIED NANOPARTICLES OF ISRADIPINE FOR IMPROVED ORAL BIOAVAILABILITY. International Journal of Applied Pharmaceutics, 15(4), 60–70. https://doi.org/10.22159/ijap.2023v15i4.4772
9. Azeez Mohammad*, Sumer Singh, Suryakanta Swain and Debashish Ghose.Current Materials Science. Quality by Design Enabled β-Cyclodextrin Complexes of Lisinopril by Kneading Method: Improved Solubility and Bioavailability, Volume 17, Issue 2, 2024 Published on: 04 May, 2023 Page: [135 - 147]Pages: 13 DOI: 10.2174/2666145416666230407100318
10. Ghose, D., Patra, C.N., Mishra, A., Jena, G.K. et al. QbD Enabled Formulation Development of Nanoemulsion of Nimodipine for Improved Biopharmaceutical Performance. J Pharm Innov 18, 1279–1297 (2023). https://doi.org/10.1007/s12247-023-09714-9